山中伸弥教授が
2006年にiPS細胞を発見し、ノーベル賞を受賞してから
Twenty years have already passed.
Meanwhile, Japan
In the same field of cell medicine
Furthermore, two Nobel laureatesIt has produced [something].
2016
東大 大隅良典教授 オートファジー
2025
阪大 坂口志文教授 制御性T細胞
But
These two technologies don't generate as much buzz as iPS cells.
iPS cells still dominate the market.
Why?
There isn't just one reason.
But I think...
It's the naming.
iPS cells.
Officially
induced pluripotent steroid cells
= induced pluripotent stem cells
Professor Yamanaka deliberately
I changed it to a lowercase "i".
at that time
Apple Inc.
iPod
iPhone
iPad
I went along with that trend.
Even though he is a professor at Kyoto University
They're good at it.
Understand the trends and win with your name.
It's a strategy.
Humans
Approximately 300 types / 60 trillion cellsIt is made of.
But originally
A single fertilized egg.
It splits and differentiates
muscle
骨
nerves
skin
Internal organs
脳
Create everything.
The fertilized egg is the ultimate pluripotent cell.
So
What if you could reset your current cells?
From there
New eyes
New bone
New nerves
Broken parts can be replaced.
The person who made that idea a reality was...
These are iPS cells.
iPS cells
• Ability to self-replicate
• Differentiation ability
Both are very high.
The risk of developing cancer is also being overcome.
And now
iPS exosomes
Cells
A signal to "repair it"They are releasing it.
Grow up
Differentiate yourself
Repair it.
That information
It is transmitted as exosomes.
This
iPS cell-derived culture supernatant
“設計図だけ”取り出したものだ。
I
Administer this.
To be honest.
I didn't feel anything.
But
This is a "seed".
It takes effect with a time delay.
Old cells are renewed
The damaged parts will be repaired.
“Returning to a body that is built correctly.
I am now
I rode in a time machine called iPS cells.
My destination is myself from 10 years ago.
AGELESS NOTE
エクソソームの本質
エクソソームの本質は細胞ではない。
It is information.
What is rejuvenation?
Instead of replacing cells
“It's a "rewrite of the design."
NEXT EPISODE
AGELESS MAN: Redesigning Aging
Aging is not something that can be stopped.
It's something that needs to be rewritten.
next time
Deactivating the aging program
*The treatments described in this blog were determined based on the diagnosis of multiple specialist physicians, not on the patient's own wishes, taking into account the patient's BMI of 27, blood pressure of 180/120, fatty liver, pre-diabetes, metabolic syndrome, and chronic generalized pain.
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