sea urchin
The first human to eat in human history was
I wonder what kind of person he was.
That appearance.
That texture
When I saw it for the first time
I don't usually eat it.
As a human instinct
The food I'm going to eat looks delicious.
Things you shouldn't eat look unappetizing.
Such biological programs
It should be built in.
But
Ignore that
Someone ate sea urchin.
And then I realized.
It's incredibly delicious.
Is that guy a sage?
or
Are you an idiot?
He must be an idiot.
That doesn't mean they're stupid.
He's the same kind of idiot as me.
My risk sensors are completely broken.
Since I turned 25
People age.
It was different before that.
It is evolving. It is being maintained.
To become complete
In order to maintain the complete form
Digestive tract
blood cell
These cells are replaced with new tissue every few days.
skin
肺
liver
It can take several weeks to several months.
Bones and muscles
It is updated every few years.
Old cells undergo apoptosis (self-destruction).
Functions integrated into genes
Disappear on your own.
Damaged cells
The immune system detects
It is removed by inflammation.
In other words
There is a mechanism to maintain a perfect state.
but,
It stops working with age.
As you get older
This system
It gradually shuts down its functions on its own.
- Cells that do not self-destruct
- New cells that are not created
The switch that maintains homeostasis
It turns off.
It's like
A restaurant at closing time.
The lights are going out one by one from the edges.
Finally
It's pitch black.
The light of fireflies.
My life is over.
That's often said.
Bad food
I don't get enough exercise.
It's stressful.
No. That's not it.
They don't understand at all.
it is
It's a program.
in advance
It will turn off when the time comes.
It is designed.
Part of the gene becomes unreadable.
By such an aging program
Everyone ages uniformly. It's unavoidable.
However, humanity now
This program
They are trying to hack.
Hacking and rewriting it.
Reprogramming.
"Biohacking"
That's what it's called.
There are several approaches.
① Rebooting genes
Clear the methylation (unreadable state).
- Demethylation
- Acetylation
- HDAC inhibitors
- Taurine, etc.
② miRNA
This is interesting.
miRNA is
It controls the switching of genes.
Which protein to produce
Which cells to activate
It controls the genes that are issuing the commands.
Over 2000 varieties!
It's contained within exosomes.
Exosomes are like
USB flash drive.
It inserts into cells.
Disseminate information.
Differentiation changes.
The division will change.
It works even on its own.
If you combine them
It creates an infinite number of possible effects.
The function of exosomes is not determined by their number.
It's the contents.
In other words
The quality of the donor.
young
health
Normal miRNA
I'll choose that.
- Umbilical cord blood
- amnion
- iPS
Exosomes derived from them.
Insert this. Insert it repeatedly.
Many times.
and,
The switch that has been turned off
Press all of them.
Homeostasis program
Wake them up by hitting them.
All floors of the elevator in the high-rise apartment building
It's the kind of thing a badly behaved kid would press all the buttons on.
Press
Press
Press it repeatedly.
turn on
turn on
turn on
and on!!!
I don't care what happens.
I also listened to the risk explanation.
I also read the paper.
I also signed the consent form.
I won't complain.
I will not object to that result!
this is
This is not a human experiment.
This is a challenge to God's program.
■ Conclusion
I'm an idiot.
But
The first person to eat sea urchin
surely
I was stupid.
That enriched the diets of humankind.
AGELESS NOTE
Aging = Program Hypothesis
Aging is not just wear and tear
Gene expression regulation abnormalities
It is explained as follows.
- Methylation
- Histone modification
- miRNA
These
“The difference between "readable state" and "unreadable state"
Switch.
In other words
Aging is
This is an error in reading the design drawings.
NEXT EPISODE
Ageless Man, transcending limits
I pressed the switch.
But
Humans have limitations.
When you exceed that
What will happen?
next time
The price of going too far
*The treatments described in this blog were determined based on the diagnosis of multiple specialist physicians, not on the patient's own wishes, taking into account the patient's BMI of 27, blood pressure of 180/120, fatty liver, pre-diabetes, metabolic syndrome, and chronic generalized pain.
[Previous and Next Articles]
Comment